Course 18F chemistry

donderdag, 23 april, 2020 tot vrijdag, 24 april, 2020

The F-18 chemistry course will be organized at the VUmc Amsterdam. 

Location: Tracer Center Amsterdam (TCA), VUmc Amsterdam
Teachers: Prof.dr. P.H. Elsinga and Prof.dr. A.D. Windhorst 

Program

Day 1.
10.00u Production of fluor-18 (Bert Windhorst)
11.00u Organic chemistry: Nucleophilic substitutions, Nucleophilic luorinations (Philip Elsinga)
11.30u Lunch
13.00u Practical aspects: Fluoride work-up, Automation, Fluorination reactions, Analyses(Bert Windhorst and Philip Elsinga)
15.00u Introduction to hands-on tomorrow
16.00u End of day 1

 

Day 2.
09.00u hands-on (4 groups of 2 persons):

  • Influence of the solvent
  • Influence of the amount of precursor
  • Influence of the position of the electron withdrawing group
  • Influence of different para positioned substituents.

12.00u Lunch
13.00u Analysis of results
14.00u Presentations and group discussion of the results
16.00u End of the training

 

Costs for participation are 100 euro, including study material. These costs have to be paid to the NKRV before the start of the course. An invoice will be send.